BDBM230233 US9340500, I-077

SMILES CC(=O)N1CCC(CC1)c1cc(C(=O)Nc2cccc(c2)C(F)(F)F)c(C)n1CCCN1CCOCC1

InChI Key InChIKey=OYBGXOBKASKPNG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230233   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM230233(US9340500, I-077)
Affinity DataKi:  2.00E+3nM ΔG°:  -8.08kcal/mole IC50:  4.70E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent